Podcast

Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each…

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Latest episodes

  1. 439: Coembedding Sequence and Structure: CLSS Maps the Protein Universe11 Aug 2026
  2. 438: Mapping AIRE: a proactive atlas of 9,790 missense variants10 Aug 2026
  3. 437: Cell villages and Dirichlet modeling map human cell fitness genetics9 Aug 2026
  4. 436: KIAP4 and the ARND family: building the Leishmania adhesion plaque8 Aug 2026
  5. 435: E. coli TGT binds two tRNAs — cryo-EM reveals dual engagement7 Aug 2026
  6. 434: High‑coverage genomes recast Japan's prehistoric demography6 Aug 2026
  7. 433: Lactate, HSP90α and the Mitochondrial Switch23 Jul 2026
  8. 432: Echovirus 18: Capsid opening releases the genome23 Jul 2026
  9. 431: KIAP4 and the ARND family: essential proteins for Leishmania–sand fly adhesion23 Jul 2026
  10. 430: Proterozoic Rise: Steady Diversification of Crown Eukaryotes23 Jul 2026